MarLo wrote:
.... I'm sure Linda H can give a far better opinion of what is going on ...
Hmmm, but she is sick and thus cranky and doesn't like most vet things.
jennifer3108 wrote:
....Within a month of getting him he was diagnosed with PKD. He was pretty underweight and his bloodwork was off and his teeth were essentially rotten. The vet put him on a kidney diet, got his bloodwork stable, got him to put on some weight, and gave him a dental.
Last weekend my sisters boyfriend, who adores the cat, gave him some dry food. It was dry kidney diet, which he hasn't eaten. He has been strictly on canned food. I guess he ended up pretty sick, with massive amounts of diarrhea, vomiting, and was drooling profusely. He was put on a bland diet and given Tylan and recovered quickly. Yesterday morning he was sick again and this time urinated on the floor. The vet gave him fluids and kept him on the Tylan/bland diet and shot for his upset stomach. He is eating ok so far. They didn't run any bloodwork this time. His heartrate was very high though. Even too high for a cat that was just nervous....
Let's backup a step or two. How was he diagnosed with PKD? Ultrasound or DNA? Or the fact the kidney values are off and he's a himi? A bloodtest will tell you the kidneys are off, but not the reason. In fact, if his teeth were really bad, that could effect the bloodwork on the kidneys. So, without either ultrasound and/or DNA, to me there's no diagnosis of PKD. And tell your sister, even if it's PKD, some cats with PKD live into their late teens, many make it to 10, so it's not a death sentence for next month or even this year. (And he can't be too far along if the vet risked anesthesia for a dental.)
The "eat something new, DROOL, vomit, diarrhea" is classic signs of food intolerance and/or food poisoning. I've said it before, but I'll say it again, some cats cannot digest dried kibble.
The high heartrate may or may not be a symptom of thyroid problems. Maggie has a "galloping" heart when stressed -- enough so that I've had ultrasounds done of her heart and there is no problems. It's stress-induced, but when rested, returns to perfect normal rate. I'm guessing this cat has a similar problem because the vet did do a dental on him. (If the heart rate was persisently high, the vet should not have put him under to do the dental.) Thyroid causes the heart to speed up, but it stays up most of the time.
Tylan is also an antibacterial for respiratory problems in cattle and swine. I know it's extensively used for cats, but for the diarrhea part there are other options. It does work to some degree with chronic diarrhea, but the cat does not have chronic diarrhea unrelated to food changes. (Just for the record, one side effect of Tylan is diarrhea.

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jennifer3108 wrote:
My sister has resumed his regular canned food from what I understand along with some canned chicken babyfood for the medication to be put in. He doesn't like to take the Tylan even in the food though. I can understand, I've gotten that stuff in my mouth and its nasty.
I also forgot to mention, he came home from the vet with alot of sneezing. It was bad enough that she mentioned it to me. I guess he also was sneezing green mucous.
I feel bad for them, both the cat and my sister and her boyfriend. This is her first real pet on her own and she's just had alot of issues with him. She adores him and just keeps asking if I think he's dying and she tells me she is getting ready for the end. Mostly she is worried about his PKD.
Green mucous is not good -- very not good! That is an upper respiratory infection or, depending on when the dental was done, an infected tooth socket that has gone into the sinuses. If he still is on the Tylan, it's not working. (Why is he still on it? Diarrhea??) Clavamox would be better for a URI. How long from vet visits to sneezing? The usual timeframe is 4-7 days for URI to appear -- could be shorter in a debilitated cat.
Here's what I would do if I were your sister: I would take him to the vet on MONDAY and ask why he's on Tylan and if he could be taken off that. Ask for Clavomox or something specific for an URI. Stick with the regular canned food, no treats or extras, for 1 month to see what his digestive problem is, if any. Get the values of his BUN and creatinine levels from the bloodwork so I know what she is dealing with in terms of kidney problems.
Tell your sister to have faith that things will turn out well. Getting a rescue kitty can be a nightmare until you know what is normal for the cat, what the cat really has, and how to deal with the problems. (I'm still figuring out Wendy!) Above all, tell your sister and her boyfriend that they are special people to take this on and to love him.